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Gene : TPS1 A. thaliana

Gene ID  ? AT1G78580
Brief Description  trehalose-6-phosphate synthase  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? trehalose-6-phosphate synthase (TPS1); CONTAINS InterPro DOMAIN/s: Alpha,alpha-trehalose-phosphate synthase (InterPro:IPR012766), Glycosyl transferase, family 20 (InterPro:IPR001830), Trehalose-phosphatase (InterPro:IPR003337); BEST Arabidopsis thaliana protein match is: trehalose-phosphatase/synthase 2 (TAIR:AT1G16980.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes an enzyme putatively involved in trehalose biosynthesis. The protein has a trehalose synthase (TPS)-like domain but no trehalose phosphatase (TPP)-like domain. ATTPS1 is able to complement yeast tps1 mutants in vivo. The gene product modulates cell growth but not cell differentiation by determining cell wall deposition and cell division.  Source: TAIR, Jun 30, 2015.
Name  ? trehalose-6-phosphate synthase
  • synonyms:
  • ATTPS1,
  • trehalose-6-phosphate synthase

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5 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
TPS1 may play a major role in coordinating cell wall biosynthesis and cell division with cellular metabolism during embryo development. 16553896
It can be expected that TPS1 from tobacco has a relatively high similarity to the TPS of Arabidopsis thaliana. 17111094
TSP1 plays an essential role in regulating the growth of vegetative as well as embryogenic tissue in a mechanism involving ABA and sugar metabolism. 20659274
loss of TPS1 causes extremely late flowering; this suggests TPS1 is required for timely initiation of flowering; findings show the trehalose-6-phosphate pathway affects flowering both in leaves and at the shoot meristem, and integrate TPS1 into the existing genetic framework of flowering-time control 23393265
Data suggest that Arabidopsis thaliana exhibits three active trehalose-6-phosphate synthase isoforms: TPS1, TPS2, and TPS4. 25495218


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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT1G78580 0.5kb upstream 0.5kb upstream 9073   true Chr1: 29552340-29561412
AT1G78580 0.5kb upstream 0.5kb upstream 500   false Chr1: 29560913-29561412
AT1G78580 0.5kb downstream 0.5kb downstream 9073   true Chr1: 29551840-29560912
AT1G78580 0.5kb downstream 0.5kb downstream 500   false Chr1: 29551840-29552339
AT1G78580 1.0kb upstream 1.0kb upstream 9573   true Chr1: 29552340-29561912
AT1G78580 1.0kb upstream 1.0kb upstream 1000   false Chr1: 29560913-29561912
AT1G78580 1.0kb downstream 1.0kb downstream 9573   true Chr1: 29551340-29560912
AT1G78580 1.0kb downstream 1.0kb downstream 1000   false Chr1: 29551340-29552339
AT1G78580 3.0kb upstream 3.0kb upstream 11573   true Chr1: 29552340-29563912
AT1G78580 3.0kb upstream 3.0kb upstream 3000   false Chr1: 29560913-29563912
AT1G78580 3.0kb downstream 3.0kb downstream 11573   true Chr1: 29549340-29560912
AT1G78580 3.0kb downstream 3.0kb downstream 3000   false Chr1: 29549340-29552339


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2 Pathways

Data Source: KEGG

Identifier Name
01100 Metabolic pathways
00500 Starch and sucrose metabolism

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10 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016