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Gene : UBC2 A. thaliana

Gene ID  ? AT2G02760
Brief Description  ubiquiting-conjugating enzyme 2  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? ubiquiting-conjugating enzyme 2 (UBC2); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: ubiquitin carrier protein 1 (TAIR:AT1G14400.2).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? ubiquitin conjugating enzyme UBC2. Homolog of the yeast RAD6 gene.  Source: TAIR, Jun 30, 2015.
Name  ? ubiquiting-conjugating enzyme 2
  • synonyms:
  • ATUBC2,
  • ubiquiting-conjugating enzyme 2

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3 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
The double mutant Atubc1-1 Atubc2-1 shows a dramatically enhanced mutant phenotype. These two genes act together with HUB1/HUB2 in H2B ubiquitylation, which is involved in the activation of floral repressor genes. 18798874
UBC1 and UBC2 redundantly mediate H2B monoubiquitination, and upregulate the expression of FLC. 18980658
The authors demonstrate that tombusvirus RNA replication and the mono- and bi-ubiquitination level of p33 is decreased in rad6Delta yeast. However, plasmid-based expression of the Arabidopsis Ubc2p could complement both defects in rad6Delta yeast. 26135843

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT2G02760 0.5kb upstream 0.5kb upstream 2758   true Chr2: 773145-775902
AT2G02760 0.5kb upstream 0.5kb upstream 500   false Chr2: 773145-773644
AT2G02760 0.5kb downstream 0.5kb downstream 2758   true Chr2: 773645-776402
AT2G02760 0.5kb downstream 0.5kb downstream 500   false Chr2: 775903-776402
AT2G02760 1.0kb upstream 1.0kb upstream 3258   true Chr2: 772645-775902
AT2G02760 1.0kb upstream 1.0kb upstream 1000   false Chr2: 772645-773644
AT2G02760 1.0kb downstream 1.0kb downstream 3258   true Chr2: 773645-776902
AT2G02760 1.0kb downstream 1.0kb downstream 1000   false Chr2: 775903-776902
AT2G02760 3.0kb upstream 3.0kb upstream 5258   true Chr2: 770645-775902
AT2G02760 3.0kb upstream 3.0kb upstream 3000   false Chr2: 770645-773644
AT2G02760 3.0kb downstream 3.0kb downstream 5258   true Chr2: 773645-778902
AT2G02760 3.0kb downstream 3.0kb downstream 3000   false Chr2: 775903-778902

Proteins

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Function

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1 Pathways

Data Source: KEGG

Identifier Name
04120 Ubiquitin mediated proteolysis

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Expression

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Interactions

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12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from GOC GO annotations assigned by the GO Consortium 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139