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Gene : ERCC1 A. thaliana

Gene ID  ? AT3G05210
Brief Description  nucleotide repair protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? ERCC1; FUNCTIONS IN: 5'-flap endonuclease activity; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), DNA repair protein rad10 (InterPro:IPR004579), RuvA domain 2-like (InterPro:IPR010994).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? encodes a homolog of human ERCC1 protein (yeast RAD10), which is a DNA repair endonuclease. Mutants are sensitive to UV-B and gamma radiation (G2 cell cycle phase arrest) and are defective in dark-repair of pyrimidine pyrimidone dimers. This protein incises the 5' end of damaged DNA, similar to ERCC1/RAD10.  Source: TAIR, Jun 30, 2015.

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1 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
ERCC1 and XPF protect short telomeres from homologous recombination. 19214203

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT3G05210 0.5kb upstream 0.5kb upstream 3204   true Chr3: 1478839-1482042
AT3G05210 0.5kb upstream 0.5kb upstream 500   false Chr3: 1478839-1479338
AT3G05210 0.5kb downstream 0.5kb downstream 3204   true Chr3: 1479339-1482542
AT3G05210 0.5kb downstream 0.5kb downstream 500   false Chr3: 1482043-1482542
AT3G05210 1.0kb upstream 1.0kb upstream 3704   true Chr3: 1478339-1482042
AT3G05210 1.0kb upstream 1.0kb upstream 1000   false Chr3: 1478339-1479338
AT3G05210 1.0kb downstream 1.0kb downstream 3704   true Chr3: 1479339-1483042
AT3G05210 1.0kb downstream 1.0kb downstream 1000   false Chr3: 1482043-1483042
AT3G05210 3.0kb upstream 3.0kb upstream 5704   true Chr3: 1476339-1482042
AT3G05210 3.0kb upstream 3.0kb upstream 3000   false Chr3: 1476339-1479338
AT3G05210 3.0kb downstream 3.0kb downstream 5704   true Chr3: 1479339-1485042
AT3G05210 3.0kb downstream 3.0kb downstream 3000   false Chr3: 1482043-1485042

Proteins

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Function

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1 Pathways

Data Source: KEGG

Identifier Name
03420 Nucleotide excision repair

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Expression

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Interactions

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Homology

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12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from InterPro    
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139