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Gene : NAP57 A. thaliana

Gene ID  ? AT3G57150
Brief Description  homologue of NAP57  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? homologue of NAP57 (NAP57); FUNCTIONS IN: pseudouridine synthase activity; INVOLVED IN: pseudouridine synthesis, RNA modification, RNA processing; LOCATED IN: cytosol, nucleolus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Pseudouridine synthase, catalytic domain (InterPro:IPR020103), Pseudouridine synthase/archaeosine transglycosylase-like (InterPro:IPR015947), Pseudouridine synthase/archaeosine transglycosylase (InterPro:IPR002478), H/ACA ribonucleoprotein complex, subunit Cbf5 (InterPro:IPR004802), Pseudouridine synthase II, TruB, N-terminal (InterPro:IPR002501), Dyskerin-like (InterPro:IPR012960), Uncharacterised domain 2 (InterPro:IPR004521); BEST Arabidopsis thaliana protein match is: Pseudouridine synthase family protein (TAIR:AT5G14460.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a putative pseudouridine synthase (NAP57).  Source: TAIR, Jun 30, 2015.
Name  ? homologue of NAP57
  • synonyms:
  • CBF5,
  • AtCBF5,
  • AtNAP57

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3 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
[CBF5] Arabidopsis CBF5 interacts with NAF1 in planta. 17712600
AtNAP57 is a conserved component of the telomerase RNP in multicellular organisms that is required for telomere maintenance. [AtNAP57] 18212040
T66A NAP57 behaves as a dominant-negative inhibitor of telomerase. dyskerin is a conserved component of the telomerase RNP complex in higher eukaryotes that is required for maximal enzyme activity in vivo. 18212040

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT3G57150 0.5kb upstream 0.5kb upstream 2761   true Chr3: 21153815-21156575
AT3G57150 0.5kb upstream 0.5kb upstream 500   false Chr3: 21156076-21156575
AT3G57150 0.5kb downstream 0.5kb downstream 2761   true Chr3: 21153315-21156075
AT3G57150 0.5kb downstream 0.5kb downstream 500   false Chr3: 21153315-21153814
AT3G57150 1.0kb upstream 1.0kb upstream 3261   true Chr3: 21153815-21157075
AT3G57150 1.0kb upstream 1.0kb upstream 1000   false Chr3: 21156076-21157075
AT3G57150 1.0kb downstream 1.0kb downstream 3261   true Chr3: 21152815-21156075
AT3G57150 1.0kb downstream 1.0kb downstream 1000   false Chr3: 21152815-21153814
AT3G57150 3.0kb upstream 3.0kb upstream 5261   true Chr3: 21153815-21159075
AT3G57150 3.0kb upstream 3.0kb upstream 3000   false Chr3: 21156076-21159075
AT3G57150 3.0kb downstream 3.0kb downstream 5261   true Chr3: 21150815-21156075
AT3G57150 3.0kb downstream 3.0kb downstream 3000   false Chr3: 21150815-21153814

Proteins

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Function

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1 Pathways

Data Source: KEGG

Identifier Name
03008 Ribosome biogenesis in eukaryotes

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Expression

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Interactions

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Homology

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Other

12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from GOC GO annotations assigned by the GO Consortium 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139