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Gene : ARGAH1 A. thaliana

Gene ID  ? AT4G08900
Brief Description  arginase  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? arginase; FUNCTIONS IN: arginase activity, cobalt ion binding, agmatinase activity; INVOLVED IN: defense response to bacterium, arginine catabolic process, polyamine metabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 8 plant structures; CONTAINS InterPro DOMAIN/s: Ureohydrolase (InterPro:IPR006035), Ureohydrolase, manganese-binding site (InterPro:IPR020855); BEST Arabidopsis thaliana protein match is: Arginase/deacetylase superfamily protein (TAIR:AT4G08870.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes an arginase, likely to be involved in polyamine biosynthesis in pollen.  Source: TAIR, Jun 30, 2015.
Name  ? arginine amidohydrolase 1

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3 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
Gene mutations within ARGAH1 or ARGAH2 are associated with increased nitric oxide signaling in root development. [ARGAH1] 18567826
The mutation of the arginase-encoding gene ARGAH2 abrogates clubroot-induced arginase activity and results in enhanced gall size in infected roots. 22433460
AtARGAHs negatively regulate many abiotic stress tolerances, at least partially, attribute to their roles in modulating arginine metabolism and reactive oxygen species accumulation. [AtARGAH1] 23378380

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G08900 0.5kb upstream 0.5kb upstream 2629   true Chr4: 5702811-5705439
AT4G08900 0.5kb upstream 0.5kb upstream 500   false Chr4: 5702811-5703310
AT4G08900 0.5kb downstream 0.5kb downstream 2629   true Chr4: 5703311-5705939
AT4G08900 0.5kb downstream 0.5kb downstream 500   false Chr4: 5705440-5705939
AT4G08900 1.0kb upstream 1.0kb upstream 3129   true Chr4: 5702311-5705439
AT4G08900 1.0kb upstream 1.0kb upstream 1000   false Chr4: 5702311-5703310
AT4G08900 1.0kb downstream 1.0kb downstream 3129   true Chr4: 5703311-5706439
AT4G08900 1.0kb downstream 1.0kb downstream 1000   false Chr4: 5705440-5706439
AT4G08900 3.0kb upstream 3.0kb upstream 5129   true Chr4: 5700311-5705439
AT4G08900 3.0kb upstream 3.0kb upstream 3000   false Chr4: 5700311-5703310
AT4G08900 3.0kb downstream 3.0kb downstream 5129   true Chr4: 5703311-5708439
AT4G08900 3.0kb downstream 3.0kb downstream 3000   false Chr4: 5705440-5708439

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Function

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5 Pathways

Data Source: KEGG

Identifier Name
01100 Metabolic pathways
01110 Biosynthesis of secondary metabolites
01230 Biosynthesis of amino acids
00220 Arginine biosynthesis
00330 Arginine and proline metabolism

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Expression

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Interactions

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12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139