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Gene : MSH4 A. thaliana

Gene ID  ? AT4G17380
Brief Description  MUTS-like protein 4  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? MUTS-like protein 4 (MSH4); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, synapsis, meiotic prophase I; LOCATED IN: condensed nuclear chromosome; EXPRESSED IN: flower, sporocyte; EXPRESSED DURING: petal differentiation and expansion stage, IL.00 inflorescence just visible; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS, core (InterPro:IPR007696); BEST Arabidopsis thaliana protein match is: MUTS homolog 2 (TAIR:AT3G18524.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes the Arabidopsis homolog of MSH4, a meiosis-specific member of the MutS-homolog family of genes. It is expressed only in floral tissues and only during early meiotic prophase I, preceding the synapsis of homologous chromosomes. It is involved in the early steps of recombination.  Source: TAIR, Jun 30, 2015.
Name  ? MUTS-like protein 4
  • synonyms:
  • ARABIDOPSIS MUTS HOMOLOG 4,
  • ATMSH4

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1 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
Localization of AtMSH5 to the chromatin at mid-prophase I is dependent on expression of AtMSH4. 18318687

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G17380 0.5kb upstream 0.5kb upstream 5952   true Chr4: 9708184-9714135
AT4G17380 0.5kb upstream 0.5kb upstream 500   false Chr4: 9708184-9708683
AT4G17380 0.5kb downstream 0.5kb downstream 5952   true Chr4: 9708684-9714635
AT4G17380 0.5kb downstream 0.5kb downstream 500   false Chr4: 9714136-9714635
AT4G17380 1.0kb upstream 1.0kb upstream 6452   true Chr4: 9707684-9714135
AT4G17380 1.0kb upstream 1.0kb upstream 1000   false Chr4: 9707684-9708683
AT4G17380 1.0kb downstream 1.0kb downstream 6452   true Chr4: 9708684-9715135
AT4G17380 1.0kb downstream 1.0kb downstream 1000   false Chr4: 9714136-9715135
AT4G17380 3.0kb upstream 3.0kb upstream 8452   true Chr4: 9705684-9714135
AT4G17380 3.0kb upstream 3.0kb upstream 3000   false Chr4: 9705684-9708683
AT4G17380 3.0kb downstream 3.0kb downstream 8452   true Chr4: 9708684-9717135
AT4G17380 3.0kb downstream 3.0kb downstream 3000   false Chr4: 9714136-9717135

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0 Pathways

Data Source: KEGG

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Expression

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10 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from RefGenome GO annotations assigned by RefGenome 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016