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Gene : DOT4 A. thaliana

Gene ID  ? AT4G18750
Brief Description  Pentatricopeptide repeat (PPR) superfamily protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? DEFECTIVELY ORGANIZED TRIBUTARIES 4 (DOT4); INVOLVED IN: cotyledon vascular tissue pattern formation, phloem or xylem histogenesis, leaf vascular tissue pattern formation, leaf development; LOCATED IN: chloroplast; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Pentatricopeptide repeat (InterPro:IPR002885); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT5G16860.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a pentatricopeptide (PPR) protein involved in leaf and root development. dot4 mutants have an aberrant midgap venation pattern in juvenile leaves and cotyledons.  Source: TAIR, Jun 30, 2015.

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1 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
DOT4 has DYW deaminase domain and is required for single RNA editing events in chloroplasts. 24194514


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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G18750 0.5kb upstream 0.5kb upstream 3512   true Chr4: 10304162-10307673
AT4G18750 0.5kb upstream 0.5kb upstream 500   false Chr4: 10304162-10304661
AT4G18750 0.5kb downstream 0.5kb downstream 3512   true Chr4: 10304662-10308173
AT4G18750 0.5kb downstream 0.5kb downstream 500   false Chr4: 10307674-10308173
AT4G18750 1.0kb upstream 1.0kb upstream 4012   true Chr4: 10303662-10307673
AT4G18750 1.0kb upstream 1.0kb upstream 1000   false Chr4: 10303662-10304661
AT4G18750 1.0kb downstream 1.0kb downstream 4012   true Chr4: 10304662-10308673
AT4G18750 1.0kb downstream 1.0kb downstream 1000   false Chr4: 10307674-10308673
AT4G18750 3.0kb upstream 3.0kb upstream 6012   true Chr4: 10301662-10307673
AT4G18750 3.0kb upstream 3.0kb upstream 3000   false Chr4: 10301662-10304661
AT4G18750 3.0kb downstream 3.0kb downstream 6012   true Chr4: 10304662-10310673
AT4G18750 3.0kb downstream 3.0kb downstream 3000   false Chr4: 10307674-10310673


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0 Pathways

Data Source: KEGG

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Array Expression

RNA-seq Expression


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9 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016