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Gene : ISU1 A. thaliana

Gene ID  ? AT4G22220
Brief Description  SufE/NifU family protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? ISU1; CONTAINS InterPro DOMAIN/s: NIF system FeS cluster assembly, NifU, N-terminal (InterPro:IPR002871), ISC system FeS cluster assembly, IscU scaffold (InterPro:IPR011339); BEST Arabidopsis thaliana protein match is: ISCU-like 3 (TAIR:AT4G04080.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a mitochondrial protein similar to E.coli IscU. In bacteria, IscU is a scaffold protein accepting sulfur and iron to build a transient Fe-S cluster,which is subsequently transferred to a target apoprotein.  Source: TAIR, Jun 30, 2015.

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2 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
ISU1 has a role in mediating the assembly of iron-sulfur clusters in mitochondria. 17417719
Results suggest that AtHscA2 in cooperation with AtIsu1 and AtHscB play an important role in the regulation of the Fe-S cluster assembly pathway in plant mitochondria. 25462017


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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G22220 0.5kb upstream 0.5kb upstream 2455   true Chr4: 11759103-11761557
AT4G22220 0.5kb upstream 0.5kb upstream 500   false Chr4: 11761058-11761557
AT4G22220 0.5kb downstream 0.5kb downstream 2455   true Chr4: 11758603-11761057
AT4G22220 0.5kb downstream 0.5kb downstream 500   false Chr4: 11758603-11759102
AT4G22220 1.0kb upstream 1.0kb upstream 2955   true Chr4: 11759103-11762057
AT4G22220 1.0kb upstream 1.0kb upstream 1000   false Chr4: 11761058-11762057
AT4G22220 1.0kb downstream 1.0kb downstream 2955   true Chr4: 11758103-11761057
AT4G22220 1.0kb downstream 1.0kb downstream 1000   false Chr4: 11758103-11759102
AT4G22220 3.0kb upstream 3.0kb upstream 4955   true Chr4: 11759103-11764057
AT4G22220 3.0kb upstream 3.0kb upstream 3000   false Chr4: 11761058-11764057
AT4G22220 3.0kb downstream 3.0kb downstream 4955   true Chr4: 11756103-11761057
AT4G22220 3.0kb downstream 3.0kb downstream 3000   false Chr4: 11756103-11759102


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0 Pathways

Data Source: KEGG

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11 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from TAIR GO annotations assigned by TAIR 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139