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Gene : AT4G33150 A. thaliana

Gene ID  ? AT4G33150
Brief Description  lysine-ketoglutarate reductase/saccharopine dehydrogenase bifunctional enzyme  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? lysine-ketoglutarate reductase/saccharopine dehydrogenase bifunctional enzyme; CONTAINS InterPro DOMAIN/s: Alanine dehydrogenase/PNT, C-terminal (InterPro:IPR007698), Saccharopine dehydrogenase / Homospermidine synthase (InterPro:IPR005097), Alanine dehydrogenase/PNT, N-terminal (InterPro:IPR007886), LOR/SDH bifunctional enzyme, conserved domain (InterPro:IPR007545).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes two proteins. One protein is the monofunctional saccharopine dehydrogenase involved in lysine degradation. The longer protein from the same LKR/SDH locus is bifunctional and also has saccharopine dehydrogenase activity. The monofunctional SDH functions mainly to enhance the flux of lysine catabolism. Gene expression is induced by abscisic acid, jasmonate, and under sucrose starvation.  Source: TAIR, Jun 30, 2015.
  • synonyms:
  • SACCHAROPINE DEHYDROGENASE,
  • LYSINE-KETOGLUTARATE REDUCTASE/SACCHAROPINE DEHYDROGENASE,
  • LKR,
  • SDH,
  • LKR/SDH

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1 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
The regulation of lysine catabolism in Arabidopsis through these two gene products of the AtLKR/SDH gene in response to various hormones and stress signals. 15569707

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G33150 0.5kb upstream 0.5kb upstream 6960   true Chr4: 15985174-15992133
AT4G33150 0.5kb upstream 0.5kb upstream 500   false Chr4: 15991634-15992133
AT4G33150 0.5kb downstream 0.5kb downstream 6960   true Chr4: 15984674-15991633
AT4G33150 0.5kb downstream 0.5kb downstream 500   false Chr4: 15984674-15985173
AT4G33150 1.0kb upstream 1.0kb upstream 7460   true Chr4: 15985174-15992633
AT4G33150 1.0kb upstream 1.0kb upstream 1000   false Chr4: 15991634-15992633
AT4G33150 1.0kb downstream 1.0kb downstream 7460   true Chr4: 15984174-15991633
AT4G33150 1.0kb downstream 1.0kb downstream 1000   false Chr4: 15984174-15985173
AT4G33150 3.0kb upstream 3.0kb upstream 9460   true Chr4: 15985174-15994633
AT4G33150 3.0kb upstream 3.0kb upstream 3000   false Chr4: 15991634-15994633
AT4G33150 3.0kb downstream 3.0kb downstream 9460   true Chr4: 15982174-15991633
AT4G33150 3.0kb downstream 3.0kb downstream 3000   false Chr4: 15982174-15985173

Proteins

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Function

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3 Pathways

Data Source: KEGG

Identifier Name
01100 Metabolic pathways
01110 Biosynthesis of secondary metabolites
00310 Lysine degradation

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Expression

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10 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from TAIR GO annotations assigned by TAIR 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
TrEMBL data set Computationally analysed records, enriched with automatic annotation 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016