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Gene : ECR1 A. thaliana

Gene ID  ? AT5G19180
Brief Description  E1 C-terminal related 1  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? E1 C-terminal related 1 (ECR1); CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), E2 binding (InterPro:IPR014929); BEST Arabidopsis thaliana protein match is: SUMO-activating enzyme 2 (TAIR:AT2G21470.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a subunit of a RUB-activating enzyme analogous to the E1 ubiquitin-activating enzyme. ECR1 functions as a heterodimer with AXR1 to activate RUB, a ubiquitin-related protein.  Source: TAIR, Jun 30, 2015.
Name  ? E1 C-terminal related 1

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2 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
The ecr1-1 mutant is resistant to the auxin-like compound indole-3-propionic acid, produces fewer lateral roots than wild type, displays reduced adult height, and stabilizes a reporter fusion protein that is degraded in response to auxin. 17449645
AXR1 and AXL1 have similar abilities to function with E1 C-TERMINAL-RELATED1 (ECR1) in catalyzing RUB1 activation and RUB1-ECR1 thioester formation. 21311953

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT5G19180 0.5kb upstream 0.5kb upstream 3286   true Chr5: 6452748-6456033
AT5G19180 0.5kb upstream 0.5kb upstream 500   false Chr5: 6452748-6453247
AT5G19180 0.5kb downstream 0.5kb downstream 3286   true Chr5: 6453248-6456533
AT5G19180 0.5kb downstream 0.5kb downstream 500   false Chr5: 6456034-6456533
AT5G19180 1.0kb upstream 1.0kb upstream 3786   true Chr5: 6452248-6456033
AT5G19180 1.0kb upstream 1.0kb upstream 1000   false Chr5: 6452248-6453247
AT5G19180 1.0kb downstream 1.0kb downstream 3786   true Chr5: 6453248-6457033
AT5G19180 1.0kb downstream 1.0kb downstream 1000   false Chr5: 6456034-6457033
AT5G19180 3.0kb upstream 3.0kb upstream 5786   true Chr5: 6450248-6456033
AT5G19180 3.0kb upstream 3.0kb upstream 3000   false Chr5: 6450248-6453247
AT5G19180 3.0kb downstream 3.0kb downstream 5786   true Chr5: 6453248-6459033
AT5G19180 3.0kb downstream 3.0kb downstream 3000   false Chr5: 6456034-6459033

Proteins

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Function

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1 Pathways

Data Source: KEGG

Identifier Name
04120 Ubiquitin mediated proteolysis

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Expression

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10 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016