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Gene : SEF A. thaliana

Gene ID  ? AT5G37055
Brief Description  HIT-type Zinc finger family protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? SERRATED LEAVES AND EARLY FLOWERING (SEF); CONTAINS InterPro DOMAIN/s: Zinc finger, HIT-type (InterPro:IPR007529).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes SERRATED LEAVES AND EARLY FLOWERING (SEF), an Arabidopsis homolog of the yeast SWC6 protein, a conserved subunit of the SWR1/SRCAP complex. SEF loss-of-function mutants have a pleiotropic phenotype characterized by serrated leaves, frequent absence of inflorescence internodes, bushy aspect, and flowers with altered number and size of organs. sef plants flower earlier than wild-type plants both under inductive and non-inductive photoperiods. SEF, ARP6 and PIE1 might form a molecular complex in Arabidopsis related to the SWR1/SRCAP complex identified in other eukaryotes.  Source: TAIR, Jun 30, 2015.
Name  ? SERRATED LEAVES AND EARLY FLOWERING
  • synonyms:
  • ATSWC6

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4 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
SERRATED LEAVES AND EARLY FLOWERING (SEF) gene represses flowering at least in part by positively regulating the expression of the FLC and MAF4 genes in A. thaliana. It interacts with ATARP6 and PIE1 to form a molecular complex. [SEF] 17142478
Arabidopsis SWC6 (AtSWC6), SUPPRESSOR OF FRIGIDA 3 (SUF3) and PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1 (PIE1) are homologs of SWC6, ARP6 and SWR1 with roles in development, including floral repression through activation of FLOWERING LOCUS C [SWC6] 17470967
part of an Arabidopsis SWR1 chromatin remodelling complex involved in the regulation of diverse aspects of plant development, including floral repression through the activation of FLC and FLC-like genes 18296430
Data indicate that mutations in genes for SWR1 complex subunits photoperiod-independent Early Flowering1 (PIE1), actin-related protein6 (ARP6), and SWR1 complex6 (SWC6) cause hypersensitivity to various DNA damaging agents. 23780875

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT5G37055 0.5kb upstream 0.5kb upstream 1572   true Chr5: 14641442-14643013
AT5G37055 0.5kb upstream 0.5kb upstream 500   false Chr5: 14642514-14643013
AT5G37055 0.5kb downstream 0.5kb downstream 1572   true Chr5: 14640942-14642513
AT5G37055 0.5kb downstream 0.5kb downstream 500   false Chr5: 14640942-14641441
AT5G37055 1.0kb upstream 1.0kb upstream 2072   true Chr5: 14641442-14643513
AT5G37055 1.0kb upstream 1.0kb upstream 1000   false Chr5: 14642514-14643513
AT5G37055 1.0kb downstream 1.0kb downstream 2072   true Chr5: 14640442-14642513
AT5G37055 1.0kb downstream 1.0kb downstream 1000   false Chr5: 14640442-14641441
AT5G37055 3.0kb upstream 3.0kb upstream 4072   true Chr5: 14641442-14645513
AT5G37055 3.0kb upstream 3.0kb upstream 3000   false Chr5: 14642514-14645513
AT5G37055 3.0kb downstream 3.0kb downstream 4072   true Chr5: 14638442-14642513
AT5G37055 3.0kb downstream 3.0kb downstream 3000   false Chr5: 14638442-14641441

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0 Pathways

Data Source: KEGG

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11 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from GOC GO annotations assigned by the GO Consortium 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139