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Gene : FBR12 A. thaliana

Gene ID  ? AT1G26630
Brief Description  Eukaryotic translation initiation factor 5A-1 (eIF-5A 1) protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? FUMONISIN B1-RESISTANT12 (FBR12); FUNCTIONS IN: translation initiation factor activity; INVOLVED IN: in 7 processes; LOCATED IN: nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Translation elongation factor, IF5A, hypusine site (InterPro:IPR019769), Translation protein SH3-like, subgroup (InterPro:IPR014722), Translation elongation factor, IF5A (InterPro:IPR001884), Translation elongation factor, IF5A C-terminal (InterPro:IPR020189), Translation protein SH3-like (InterPro:IPR008991), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), KOW (InterPro:IPR005824); BEST Arabidopsis thaliana protein match is: eukaryotic elongation factor 5A-3 (TAIR:AT1G69410.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Eukaryotic translation initiation factor 5A-2. Involved in programmed cell death triggered as a response to pseudomonas syringae infection. Loss of function mutants are more resistant to infection.  Source: TAIR, Jun 30, 2015.
  • synonyms:
  • ELF5A-2,
  • ATELF5A-2

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4 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
fundamental for plant growth and development by regulating cell division, cell growth, and cell death 17513484
key element of the signal transduction pathway resulting in plant programmed cell death 18633122
Crystal structure of Arabidopsis translation initiation factor eIF-5A2 19676114
FBR12/eIF5A-2 is involved in cytokinin signaling to directly regulate root protoxylem specification 24163315


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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT1G26630 0.5kb upstream 0.5kb upstream 2118   true Chr1: 9205300-9207417
AT1G26630 0.5kb upstream 0.5kb upstream 500   false Chr1: 9205300-9205799
AT1G26630 0.5kb downstream 0.5kb downstream 2118   true Chr1: 9205800-9207917
AT1G26630 0.5kb downstream 0.5kb downstream 500   false Chr1: 9207418-9207917
AT1G26630 1.0kb upstream 1.0kb upstream 2618   true Chr1: 9204800-9207417
AT1G26630 1.0kb upstream 1.0kb upstream 1000   false Chr1: 9204800-9205799
AT1G26630 1.0kb downstream 1.0kb downstream 2618   true Chr1: 9205800-9208417
AT1G26630 1.0kb downstream 1.0kb downstream 1000   false Chr1: 9207418-9208417
AT1G26630 3.0kb upstream 3.0kb upstream 4618   true Chr1: 9202800-9207417
AT1G26630 3.0kb upstream 3.0kb upstream 3000   false Chr1: 9202800-9205799
AT1G26630 3.0kb downstream 3.0kb downstream 4618   true Chr1: 9205800-9210417
AT1G26630 3.0kb downstream 3.0kb downstream 3000   false Chr1: 9207418-9210417


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0 Pathways

Data Source: KEGG

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11 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from TIGR GO annotations assigned by TIGR Arabidopsis annotation effort 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139