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Gene : FWA A. thaliana

Gene ID  ? AT4G25530
Brief Description  FLOWERING WAGENINGEN  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? FLOWERING WAGENINGEN (FWA); CONTAINS InterPro DOMAIN/s: Homeobox (InterPro:IPR001356), Homeodomain-like (InterPro:IPR009057), Lipid-binding START (InterPro:IPR002913), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: homeodomain GLABROUS 7 (TAIR:AT5G52170.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a homeodomain-containing transcription factor that controls flowering. FWA is silenced in wild type plants and reverse of the imprinted silencing causes a late flowering phenotype. FWA gene contains two tandem repeats around the transcription start site that are necessary and sufficient for silencing via DNA methylation.  Source: TAIR, Jun 30, 2015.
Name  ? FLOWERING WAGENINGEN
  • synonyms:
  • HOMEODOMAIN GLABROUS 6,
  • HDG6

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6 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
The mechanisms of FWA silencing were studied. 17144899
Specific interaction of FWA with FT enabled us to use FWA protein as a specific inhibitor of FT protein function 17189287
Data show that the expression of FWA was repressed by Arabidopsis relatives of the human lysine-specific Demethylase1 and thus promote the floral transition. 17921315
the tandem repeat structure is dispensable for the epigenetic silencing of the FWA gene 18389059
Vegetative expression of the A. thaliana FWA gene causes late flowering. 21457364
Inflorescence abnormalities in plants overexpressing the Arabidopsis lyrata FT (AlFT) and A. thaliana FWA (AtFWA) genes simultaneously, were studied. 21889057

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G25530 0.5kb upstream 0.5kb upstream 4605   true Chr4: 13037860-13042464
AT4G25530 0.5kb upstream 0.5kb upstream 500   false Chr4: 13037860-13038359
AT4G25530 0.5kb downstream 0.5kb downstream 4605   true Chr4: 13038360-13042964
AT4G25530 0.5kb downstream 0.5kb downstream 500   false Chr4: 13042465-13042964
AT4G25530 1.0kb upstream 1.0kb upstream 5105   true Chr4: 13037360-13042464
AT4G25530 1.0kb upstream 1.0kb upstream 1000   false Chr4: 13037360-13038359
AT4G25530 1.0kb downstream 1.0kb downstream 5105   true Chr4: 13038360-13043464
AT4G25530 1.0kb downstream 1.0kb downstream 1000   false Chr4: 13042465-13043464
AT4G25530 3.0kb upstream 3.0kb upstream 7105   true Chr4: 13035360-13042464
AT4G25530 3.0kb upstream 3.0kb upstream 3000   false Chr4: 13035360-13038359
AT4G25530 3.0kb downstream 3.0kb downstream 7105   true Chr4: 13038360-13045464
AT4G25530 3.0kb downstream 3.0kb downstream 3000   false Chr4: 13042465-13045464

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0 Pathways

Data Source: KEGG

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11 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139