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Gene : TCTP A. thaliana

Gene ID  ? AT3G16640
Brief Description  translationally controlled tumor protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? translationally controlled tumor protein (TCTP); INVOLVED IN: in 8 processes; LOCATED IN: in 6 components; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Translationally controlled tumour protein (InterPro:IPR018105), Mss4/translationally controlled tumour-associated TCTP (InterPro:IPR011323), Translationally controlled tumour protein, conserved site (InterPro:IPR018103), Mss4-like (InterPro:IPR011057); BEST Arabidopsis thaliana protein match is: Methionine sulfoxide reductase (MSS4-like) family protein (TAIR:AT3G05540.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a protein homologous to translationally controlled tumor protein (TCTP) from Drosophila. In flies, TCTP functions guanine nucleotide exchange factor in the TOR signaling pathway. TCTP is expressed throughout the plant with highest levels seen in meristematic regions of the shoot and root. Loss of function alleles are not transmitted through the male gametophyte due to defects in pollen tube growth. Hypomorphs, generated through RNAi, are dwarf and have smaller cells. These plants also have defects in lateral and primary root growth as well as root hair growth. The phenotypes are similar to TOR mutants suggesting that TCTP functions in the is pathway in Arabidopsis as well.  Source: TAIR, Jun 30, 2015.
Name  ? translationally controlled tumor protein
  • synonyms:
  • AtTCTP2

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4 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
The results identify TCTP as an important regulator of growth in plants and imply a function of plant TCTP as a mediator of TOR activity similar to that known in nonplant systems. 19060111
data support a role of plant AtTCTP as a positive regulator of mitotic growth by specifically controlling the duration of the cell cycle. 20736351
TCTP has molecular properties similar to animal TCTPs, such as tubulin- and calcium-binding, and that it functions in ABA-mediated stomatal movement, in addition to regulating the growth of plants. 22610367
The 0.3 kb AtTCTP promoter can be used as a plant-derived constitutive promoter for the expression of selectable marker genes, which facilitates its use as an alternative to the 35S promoter for developing genetically engineered crops. 25410250

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT3G16640 0.5kb upstream 0.5kb upstream 2026   true Chr3: 5669317-5671342
AT3G16640 0.5kb upstream 0.5kb upstream 500   false Chr3: 5670843-5671342
AT3G16640 0.5kb downstream 0.5kb downstream 2026   true Chr3: 5668817-5670842
AT3G16640 0.5kb downstream 0.5kb downstream 500   false Chr3: 5668817-5669316
AT3G16640 1.0kb upstream 1.0kb upstream 2526   true Chr3: 5669317-5671842
AT3G16640 1.0kb upstream 1.0kb upstream 1000   false Chr3: 5670843-5671842
AT3G16640 1.0kb downstream 1.0kb downstream 2526   true Chr3: 5668317-5670842
AT3G16640 1.0kb downstream 1.0kb downstream 1000   false Chr3: 5668317-5669316
AT3G16640 3.0kb upstream 3.0kb upstream 4526   true Chr3: 5669317-5673842
AT3G16640 3.0kb upstream 3.0kb upstream 3000   false Chr3: 5670843-5673842
AT3G16640 3.0kb downstream 3.0kb downstream 4526   true Chr3: 5666317-5670842
AT3G16640 3.0kb downstream 3.0kb downstream 3000   false Chr3: 5666317-5669316

Proteins

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0 Pathways

Data Source: KEGG

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11 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from GOC GO annotations assigned by the GO Consortium 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139