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Gene : HSC70-1 A. thaliana

Gene ID  ? AT5G02500
Brief Description  heat shock cognate protein 70-1  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? heat shock cognate protein 70-1 (HSC70-1); FUNCTIONS IN: ATP binding; INVOLVED IN: protein folding, response to cadmium ion, response to cold, response to virus, response to heat; LOCATED IN: in 9 components; EXPRESSED IN: 29 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock protein 70, conserved site (InterPro:IPR018181), Heat shock protein Hsp70 (InterPro:IPR001023), Heat shock protein 70 (InterPro:IPR013126); BEST Arabidopsis thaliana protein match is: Heat shock protein 70 (Hsp 70) family protein (TAIR:AT5G02490.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? encodes a member of heat shock protein 70 family.  Source: TAIR, Jun 30, 2015.
Name  ? heat shock cognate protein 70-1
  • synonyms:
  • AT-HSC70-1,
  • HSC70,
  • HSP70-1,
  • AtHsp70-1

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3 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
Data conclude that an HSC70-SGT1 chaperone complex is important for multiple plant environmental responses and that the evolutionarily conserved SGS domain of SGT1 is a key determinant of the HSC70-SGT1 association. 18065690
HSC70-1 is involved in development and abiotic stress responses in Arabidopsis. 19443614
These data suggest that both HSC70-1 and the WPP-domain proteins play a role in facilitating WIT1 nuclear envelope targeting; this may be the first described in planta activity for the WPP-domain proteins. 19617588


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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT5G02500 0.5kb upstream 0.5kb upstream 3379   true Chr5: 553745-557123
AT5G02500 0.5kb upstream 0.5kb upstream 500   false Chr5: 556624-557123
AT5G02500 0.5kb downstream 0.5kb downstream 3379   true Chr5: 553245-556623
AT5G02500 0.5kb downstream 0.5kb downstream 500   false Chr5: 553245-553744
AT5G02500 1.0kb upstream 1.0kb upstream 3879   true Chr5: 553745-557623
AT5G02500 1.0kb upstream 1.0kb upstream 1000   false Chr5: 556624-557623
AT5G02500 1.0kb downstream 1.0kb downstream 3879   true Chr5: 552745-556623
AT5G02500 1.0kb downstream 1.0kb downstream 1000   false Chr5: 552745-553744
AT5G02500 3.0kb upstream 3.0kb upstream 5879   true Chr5: 553745-559623
AT5G02500 3.0kb upstream 3.0kb upstream 3000   false Chr5: 556624-559623
AT5G02500 3.0kb downstream 3.0kb downstream 5879   true Chr5: 550745-556623
AT5G02500 3.0kb downstream 3.0kb downstream 3000   false Chr5: 550745-553744


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3 Pathways

Data Source: KEGG

Identifier Name
04144 Endocytosis
03040 Spliceosome
04141 Protein processing in endoplasmic reticulum

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12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139