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Gene : GAPC1 A. thaliana

Gene ID  ? AT3G04120
Brief Description  glyceraldehyde-3-phosphate dehydrogenase C subunit 1  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? glyceraldehyde-3-phosphate dehydrogenase C subunit 1 (GAPC1); FUNCTIONS IN: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity, copper ion binding, glyceraldehyde-3-phosphate dehydrogenase activity; INVOLVED IN: in 11 processes; LOCATED IN: in 8 components; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Glyceraldehyde 3-phosphate dehydrogenase family (InterPro:IPR020831), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain (InterPro:IPR020829), Glyceraldehyde 3-phosphate dehydrogenase subfamily (InterPro:IPR000173), Glyceraldehyde-3-phosphate dehydrogenase, type I (InterPro:IPR006424), Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup (InterPro:IPR020832), Glyceraldehyde 3-phosphate dehydrogenase, active site (InterPro:IPR020830), Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain (InterPro:IPR020828); BEST Arabidopsis thaliana protein match is: glyceraldehyde-3-phosphate dehydrogenase C2 (TAIR:AT1G13440.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? encodes cytosolic GADPH (C subunit) involved in the glycolytic pathway but also interacts with H2O2 potentially placing it in a signalling cascade induced by ROS.  Source: TAIR, Jun 30, 2015.
Name  ? glyceraldehyde-3-phosphate dehydrogenase C subunit 1
  • synonyms:
  • GAPC,
  • GAPC-1,
  • GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE C SUBUNIT

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6 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
The addition of GSSG, and much more efficiently of S-nitrosoglutathione, was shown to inactivate the enzymes GapC1 and GapC2 from Arabidopsis thaliana, spinach, yeast and rabbit muscle. [GapC1] 18298409
Results indicate that the H(2)O(2)-promoted interaction of GAPC and PLDdelta may provide a direct connection between membrane lipid-based signaling, energy metabolism and growth control in the plant response to ROS and water stress. 22589465
Glycolytic GAPC1, through its high sensitivity to the cellular redox state, may play a role in oxidative stress signaling or protection in plants. 23569110
GAPC levels play important roles in the overall cellular production of reductants, energy, and carbohydrate metabolites and that GAPC levels are directly correlated with seed oil accumulation. 24989043
After perception of bacterial flagellin, GAPC1 dynamically responded with a significant increase in size of fluorescent puncta and enhanced nuclear accumulation 25918875
FERONIA controls leaf starch accumulation by interacting with GAPC1. 26232644

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT3G04120 0.5kb upstream 0.5kb upstream 3249   true Chr3: 1080442-1083690
AT3G04120 0.5kb upstream 0.5kb upstream 500   false Chr3: 1080442-1080941
AT3G04120 0.5kb downstream 0.5kb downstream 3249   true Chr3: 1080942-1084190
AT3G04120 0.5kb downstream 0.5kb downstream 500   false Chr3: 1083691-1084190
AT3G04120 1.0kb upstream 1.0kb upstream 3749   true Chr3: 1079942-1083690
AT3G04120 1.0kb upstream 1.0kb upstream 1000   false Chr3: 1079942-1080941
AT3G04120 1.0kb downstream 1.0kb downstream 3749   true Chr3: 1080942-1084690
AT3G04120 1.0kb downstream 1.0kb downstream 1000   false Chr3: 1083691-1084690
AT3G04120 3.0kb upstream 3.0kb upstream 5749   true Chr3: 1077942-1083690
AT3G04120 3.0kb upstream 3.0kb upstream 3000   false Chr3: 1077942-1080941
AT3G04120 3.0kb downstream 3.0kb downstream 5749   true Chr3: 1080942-1086690
AT3G04120 3.0kb downstream 3.0kb downstream 3000   false Chr3: 1083691-1086690

Proteins

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6 Pathways

Data Source: KEGG

Identifier Name
00010 Glycolysis / Gluconeogenesis
01100 Metabolic pathways
01110 Biosynthesis of secondary metabolites
01200 Carbon metabolism
01230 Biosynthesis of amino acids
00710 Carbon fixation in photosynthetic organisms

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Expression

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Interactions

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12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139