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Gene : SHD A. thaliana

Gene ID  ? AT4G24190
Brief Description  Chaperone protein htpG family protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? SHEPHERD (SHD); FUNCTIONS IN: unfolded protein binding, ATP binding; INVOLVED IN: in 8 processes; LOCATED IN: in 7 components; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Chaperone protein htpG (InterPro:IPR001404), Heat shock protein Hsp90, C-terminal (InterPro:IPR020576), Heat shock protein Hsp90, N-terminal (InterPro:IPR020575), Molecular chaperone, heat shock protein, endoplasmin (InterPro:IPR015566), ATPase-like, ATP-binding domain (InterPro:IPR003594), Heat shock protein Hsp90, conserved site (InterPro:IPR019805), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568); BEST Arabidopsis thaliana protein match is: heat shock protein 90.1 (TAIR:AT5G52640.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? encodes an ortholog of GRP94, an ER-resident HSP90-like protein and is involved in regulation of meristem size and organization. Single and double mutant analyses suggest that SHD may be required for the correct folding and/or complex formation of CLV proteins. Lines carrying recessive mutations in this locus exhibits expanded shoot meristems, disorganized root meristems, and defective pollen tube elongation. Transcript is detected in all tissues examined and is not induced by heat. Endoplasmin supports the protein secretory pathway and has a role in proliferating tissues.  Source: TAIR, Jun 30, 2015.
Name  ? SHEPHERD
  • synonyms:
  • AtHsp90-7,
  • AtHsp90.7,
  • HEAT SHOCK PROTEIN 90.7,
  • HEAT SHOCK PROTEIN 90.7,
  • HEAT SHOCK PROTEIN 90-7,
  • HSP90.7

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2 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
Results show that the induction expression of ABA-responsive genes under salt and drought stress was delayed by constitutive overexpression of cytosolic AtHsp90.2, but was hardly affected by that of organellar AtHsp90.5 and AtHsp90.7. 19148673
Seedlings expressing HSP90.7(Delta22) had enhanced sensitivity to ER stress induced by tunicamycin or high concentration of calcium. Its general chaperone activity in preventing the model protein from heat-induced aggregation was not significantly affected. 25297550

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G24190 0.5kb upstream 0.5kb upstream 5007   true Chr4: 12551552-12556558
AT4G24190 0.5kb upstream 0.5kb upstream 500   false Chr4: 12556059-12556558
AT4G24190 0.5kb downstream 0.5kb downstream 5007   true Chr4: 12551052-12556058
AT4G24190 0.5kb downstream 0.5kb downstream 500   false Chr4: 12551052-12551551
AT4G24190 1.0kb upstream 1.0kb upstream 5507   true Chr4: 12551552-12557058
AT4G24190 1.0kb upstream 1.0kb upstream 1000   false Chr4: 12556059-12557058
AT4G24190 1.0kb downstream 1.0kb downstream 5507   true Chr4: 12550552-12556058
AT4G24190 1.0kb downstream 1.0kb downstream 1000   false Chr4: 12550552-12551551
AT4G24190 3.0kb upstream 3.0kb upstream 7507   true Chr4: 12551552-12559058
AT4G24190 3.0kb upstream 3.0kb upstream 3000   false Chr4: 12556059-12559058
AT4G24190 3.0kb downstream 3.0kb downstream 7507   true Chr4: 12548552-12556058
AT4G24190 3.0kb downstream 3.0kb downstream 3000   false Chr4: 12548552-12551551

Proteins

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2 Pathways

Data Source: KEGG

Identifier Name
04626 Plant-pathogen interaction
04141 Protein processing in endoplasmic reticulum

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Expression

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12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139