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Gene : MKK6 A. thaliana

Gene ID  ? AT5G56580
Brief Description  MAP kinase kinase 6  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? MAP kinase kinase 6 (MKK6); FUNCTIONS IN: MAP kinase kinase activity, kinase activity; INVOLVED IN: protein amino acid phosphorylation; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: MAP kinase kinase 2 (TAIR:AT4G29810.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a member of the MAP Kinase Kinase family of proteins. It can phosphorylate MPK12 in vitro and it can be dephosphorylated by MKP2 in vitro.  Source: TAIR, Jun 30, 2015.
Name  ? MAP kinase kinase 6
  • synonyms:
  • ANQ1,
  • ATMKK6,
  • ARABIDOPSIS NQK1,
  • ARABIDOPSIS THALIANA MAP KINASE KINASE 6

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3 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
Plants with mutations in the MKK6/ANQ gene exhibit severe defects in cytokinesis. 20802223
Arabidopsis MPK4 can interact with and be phosphorylated by the cytokinesis-related MAP kinase kinase, AtMKK6. 21575092
AtMKK6-AtMPK13 module positively regulates lateral root formation. 21904115

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT5G56580 0.5kb upstream 0.5kb upstream 2643   true Chr5: 22904622-22907264
AT5G56580 0.5kb upstream 0.5kb upstream 500   false Chr5: 22906765-22907264
AT5G56580 0.5kb downstream 0.5kb downstream 2643   true Chr5: 22904122-22906764
AT5G56580 0.5kb downstream 0.5kb downstream 500   false Chr5: 22904122-22904621
AT5G56580 1.0kb upstream 1.0kb upstream 3143   true Chr5: 22904622-22907764
AT5G56580 1.0kb upstream 1.0kb upstream 1000   false Chr5: 22906765-22907764
AT5G56580 1.0kb downstream 1.0kb downstream 3143   true Chr5: 22903622-22906764
AT5G56580 1.0kb downstream 1.0kb downstream 1000   false Chr5: 22903622-22904621
AT5G56580 3.0kb upstream 3.0kb upstream 5143   true Chr5: 22904622-22909764
AT5G56580 3.0kb upstream 3.0kb upstream 3000   false Chr5: 22906765-22909764
AT5G56580 3.0kb downstream 3.0kb downstream 5143   true Chr5: 22901622-22906764
AT5G56580 3.0kb downstream 3.0kb downstream 3000   false Chr5: 22901622-22904621

Proteins

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Function

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1 Pathways

Data Source: KEGG

Identifier Name
04626 Plant-pathogen interaction

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Expression

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Interactions

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Stocks

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Other

12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from GOC GO annotations assigned by the GO Consortium 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139