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Gene : FRK1 A. thaliana

Gene ID  ? AT2G19190
Brief Description  FLG22-induced receptor-like kinase 1  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? FLG22-induced receptor-like kinase 1 (FRK1); FUNCTIONS IN: kinase activity; INVOLVED IN: defense response to bacterium; LOCATED IN: endomembrane system; EXPRESSED IN: stem, sepal, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat transmembrane protein kinase protein (TAIR:AT4G29990.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a receptor-like protein kinase that is involved in early defense signaling. Expression of this gene is strongly induced during leaf senescence. It is a target of the transcription factor AtWRKY6.  Source: TAIR, Jun 30, 2015.
Name  ? FLG22-induced receptor-like kinase 1
  • synonyms:
  • se- nescence-induced receptor-like kinase,
  • SIRK

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2 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
Data indicate that WRKY22 T-DNA insertion mutants wrky22-1 and wrky22-2 had lower disease resistance and lower induction of innate immunity markers, such as FLG22-INDUCED RECEPTOR-LIKE KINASE1 (FRK1) and WRKY53, after submergence. 23897923
we describe a luminol-based ROS Re-elicitation Assay that can be utilized to quantitatively assess flg22-signaling competency of FLS2 at times during which FLS2 is internalized, trafficked through endosomal compartments, and degraded in response to flg22 25117282

Genomics

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT2G19190 0.5kb upstream 0.5kb upstream 4396   true Chr2: 8326049-8330444
AT2G19190 0.5kb upstream 0.5kb upstream 500   false Chr2: 8329945-8330444
AT2G19190 0.5kb downstream 0.5kb downstream 4396   true Chr2: 8325549-8329944
AT2G19190 0.5kb downstream 0.5kb downstream 500   false Chr2: 8325549-8326048
AT2G19190 1.0kb upstream 1.0kb upstream 4896   true Chr2: 8326049-8330944
AT2G19190 1.0kb upstream 1.0kb upstream 1000   false Chr2: 8329945-8330944
AT2G19190 1.0kb downstream 1.0kb downstream 4896   true Chr2: 8325049-8329944
AT2G19190 1.0kb downstream 1.0kb downstream 1000   false Chr2: 8325049-8326048
AT2G19190 3.0kb upstream 3.0kb upstream 6896   true Chr2: 8326049-8332944
AT2G19190 3.0kb upstream 3.0kb upstream 3000   false Chr2: 8329945-8332944
AT2G19190 3.0kb downstream 3.0kb downstream 6896   true Chr2: 8323049-8329944
AT2G19190 3.0kb downstream 3.0kb downstream 3000   false Chr2: 8323049-8326048

Proteins

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1 Pathways

Data Source: KEGG

Identifier Name
04626 Plant-pathogen interaction

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11 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139