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Gene : CAM1 A. thaliana

Gene ID  ? AT5G37780
Brief Description  calmodulin 1  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? calmodulin 1 (CAM1); FUNCTIONS IN: calcium ion binding; INVOLVED IN: detection of calcium ion, response to mechanical stimulus; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248); BEST Arabidopsis thaliana protein match is: calmodulin 4 (TAIR:AT1G66410.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? encodes a calmodulin that is involved in thigmomorphogenesis. Gene expression is rapidly induced upon a variety of abiotic stimuli, including water spray, subirrigation, wind, touch, wounding, or darkness.  Source: TAIR, Jun 30, 2015.
Name  ? calmodulin 1
  • synonyms:
  • ACAM-1,
  • TOUCH 1,
  • TCH1

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5 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
the cytosolic face of ACA8 mediates early CaM recognition and CaM subsequently competes with the intramolecular autoinhibitor in binding to the other face of the helix 16267044
Data show that the level of CAM1 and CAM5 gene mRNAs were consistently greater in response to heat stress in both root and shoot. 20554213
Ca(2+)/Calmodulin-mediated signaling regulates plant response to herbivore attack/wounding by modulating the salicylic acid-jasmonic acid crosstalk through AtSR1. 22371088
the PPIase activity of the Arabidopsis cyclophilin was not affected by CaM 26317213
mutations in the two lobes affect GAD1 activation in similar ways and only intact AtCaM1 can fully activate GAD1. Taken together, our data provide new insights into the CaM lobes role in interactions between CaM and plant GAD. 26708477


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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT5G37780 0.5kb upstream 0.5kb upstream 2302   true Chr5: 15004466-15006767
AT5G37780 0.5kb upstream 0.5kb upstream 500   false Chr5: 15006268-15006767
AT5G37780 0.5kb downstream 0.5kb downstream 2302   true Chr5: 15003966-15006267
AT5G37780 0.5kb downstream 0.5kb downstream 500   false Chr5: 15003966-15004465
AT5G37780 1.0kb upstream 1.0kb upstream 2802   true Chr5: 15004466-15007267
AT5G37780 1.0kb upstream 1.0kb upstream 1000   false Chr5: 15006268-15007267
AT5G37780 1.0kb downstream 1.0kb downstream 2802   true Chr5: 15003466-15006267
AT5G37780 1.0kb downstream 1.0kb downstream 1000   false Chr5: 15003466-15004465
AT5G37780 3.0kb upstream 3.0kb upstream 4802   true Chr5: 15004466-15009267
AT5G37780 3.0kb upstream 3.0kb upstream 3000   false Chr5: 15006268-15009267
AT5G37780 3.0kb downstream 3.0kb downstream 4802   true Chr5: 15001466-15006267
AT5G37780 3.0kb downstream 3.0kb downstream 3000   false Chr5: 15001466-15004465


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2 Pathways

Data Source: KEGG

Identifier Name
04626 Plant-pathogen interaction
04070 Phosphatidylinositol signaling system

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12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from InterPro    
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139