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Gene : SGT1A A. thaliana

Gene ID  ? AT4G23570
Brief Description  phosphatase-like protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? SGT1A; FUNCTIONS IN: protein binding; INVOLVED IN: defense response, ubiquitin-dependent protein catabolic process, embryo development ending in seed dormancy; LOCATED IN: SCF ubiquitin ligase complex, nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), SGS (InterPro:IPR007699), HSP20-like chaperone (InterPro:IPR008978), CS domain (InterPro:IPR017447), CS-like domain (InterPro:IPR007052), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: phosphatase-related (TAIR:AT4G11260.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Closely related to SGT1B, may function in SCF(TIR1) mediated protein degradation. AtSGT1a and AtSGT1b are functionally redundant in the resistance to pathogenes. AtSGT1b was more highly expressed than AtSGT1. The N-terminal TPR domain of AtSGT1a reduces the steady-state level of Arabidopsis SGT1 proteins whereas the same domain from AtSGT1b enhances SGT1 accumulation. The TPR domain is dispensable for SGT1 resistance. AtSGT1a is induced upon pathogen infection and can function in R gene-mediated resistance.  Source: TAIR, Jun 30, 2015.

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1 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
Nuclear magnetic resonance spectroscopy and mutational analyses of HSP90 revealed the nature of its binding with the CS domain of SGT1. 18833289

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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G23570 0.5kb upstream 0.5kb upstream 3687   true Chr4: 12299249-12302935
AT4G23570 0.5kb upstream 0.5kb upstream 500   false Chr4: 12299249-12299748
AT4G23570 0.5kb downstream 0.5kb downstream 3687   true Chr4: 12299749-12303435
AT4G23570 0.5kb downstream 0.5kb downstream 500   false Chr4: 12302936-12303435
AT4G23570 1.0kb upstream 1.0kb upstream 4187   true Chr4: 12298749-12302935
AT4G23570 1.0kb upstream 1.0kb upstream 1000   false Chr4: 12298749-12299748
AT4G23570 1.0kb downstream 1.0kb downstream 4187   true Chr4: 12299749-12303935
AT4G23570 1.0kb downstream 1.0kb downstream 1000   false Chr4: 12302936-12303935
AT4G23570 3.0kb upstream 3.0kb upstream 6187   true Chr4: 12296749-12302935
AT4G23570 3.0kb upstream 3.0kb upstream 3000   false Chr4: 12296749-12299748
AT4G23570 3.0kb downstream 3.0kb downstream 6187   true Chr4: 12299749-12305935
AT4G23570 3.0kb downstream 3.0kb downstream 3000   false Chr4: 12302936-12305935

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1 Pathways

Data Source: KEGG

Identifier Name
04626 Plant-pathogen interaction

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12 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from TAIR GO annotations assigned by TAIR 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
KEGG pathways data set Wiring diagrams of molecular interactions, reactions, and relations 79.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
IntAct interactions data set Curated binary and complex protein-protein interactions for Arabidopsis thaliana 8/02/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139