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Gene : MKP2 A. thaliana

Gene ID  ? AT3G06110
Brief Description  MAPK phosphatase 2  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? MAPK phosphatase 2 (MKP2); FUNCTIONS IN: MAP kinase phosphatase activity, protein tyrosine/serine/threonine phosphatase activity; INVOLVED IN: intracellular protein kinase cascade, response to ozone, negative regulation of MAP kinase activity, response to stress; LOCATED IN: nucleus, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase 1 (TAIR:AT3G23610.2).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? Encodes a nuclear-localized MAP kinase phosphatase. Plants with reduced levels of MKP2 transcripts are hypersensitive to ozone and ozone-mediated activation of MPK3 and MPK6 is prolonged in these plants.  Source: TAIR, Jun 30, 2015.
Name  ? MAPK phosphatase 2
  • synonyms:
  • DSPTP1B,
  • ATMKP2,

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2 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
This study describes the interplay of MAPK and MKP2 phosphatase signaling during cell death responses elicited by host-pathogen interactions.[MKP2] 21057191
silencing promoted early leaf senescence 22709441


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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT3G06110 0.5kb upstream 0.5kb upstream 2150   true Chr3: 1842913-1845062
AT3G06110 0.5kb upstream 0.5kb upstream 500   false Chr3: 1842913-1843412
AT3G06110 0.5kb downstream 0.5kb downstream 2150   true Chr3: 1843413-1845562
AT3G06110 0.5kb downstream 0.5kb downstream 500   false Chr3: 1845063-1845562
AT3G06110 1.0kb upstream 1.0kb upstream 2650   true Chr3: 1842413-1845062
AT3G06110 1.0kb upstream 1.0kb upstream 1000   false Chr3: 1842413-1843412
AT3G06110 1.0kb downstream 1.0kb downstream 2650   true Chr3: 1843413-1846062
AT3G06110 1.0kb downstream 1.0kb downstream 1000   false Chr3: 1845063-1846062
AT3G06110 3.0kb upstream 3.0kb upstream 4650   true Chr3: 1840413-1845062
AT3G06110 3.0kb upstream 3.0kb upstream 3000   false Chr3: 1840413-1843412
AT3G06110 3.0kb downstream 3.0kb downstream 4650   true Chr3: 1843413-1848062
AT3G06110 3.0kb downstream 3.0kb downstream 3000   false Chr3: 1845063-1848062


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0 Pathways

Data Source: KEGG

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10 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139