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Gene : VEP1 A. thaliana

Gene ID  ? AT4G24220
Brief Description  NAD(P)-binding Rossmann-fold superfamily protein  Source: Araport11 (06/2016).
Is Obsolete?  false
Computational Description  ? VEIN PATTERNING 1 (VEP1); FUNCTIONS IN: binding, catalytic activity; INVOLVED IN: xylem and phloem pattern formation, response to wounding; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD(P)-binding Rossmann-fold superfamily protein (TAIR:AT5G58750.1).  Source: TAIR, Jun 30, 2015.
Curator Summary  ? encodes a progesterone-5beta-reductase-like protein. It has enone reductase activity against a wide range of substrates, including 3-oxo-Δ-4,5-steroids in vitro. The in vivo substrates and product of this enzyme have not yet been elucidated but it is likely to participate in steroid metabolism. The protein contains a mammalian death domain involved in programmed cell death. The gene is expressed in the vascular system and mutants carrying a dominant mutation in the gene have defective vascular patterning. VEP1 gene expression is induced specifically by wounding.  Source: TAIR, Jun 30, 2015.
  • synonyms:
  • 5[beta]-StR,
  • AWI31,
  • Δ4%2C5-steroid-5[beta]-reductase

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1 GeneRIFs (Gene References Into Functions)

Data Source: NCBI

Annotation PubMed Id
The gene VEP1 encoding At5beta-StR was strongly transcribed in stems and leaves. 19166903


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12 Flanking Regions

Flank size: from most upstream transcription start site, or most downstream transcription stop site

Region Name Flank Size Direction Length Gene Included? Chromosome Location
AT4G24220 0.5kb upstream 0.5kb upstream 2311   true Chr4: 12564445-12566755
AT4G24220 0.5kb upstream 0.5kb upstream 500   false Chr4: 12564445-12564944
AT4G24220 0.5kb downstream 0.5kb downstream 2311   true Chr4: 12564945-12567255
AT4G24220 0.5kb downstream 0.5kb downstream 500   false Chr4: 12566756-12567255
AT4G24220 1.0kb upstream 1.0kb upstream 2811   true Chr4: 12563945-12566755
AT4G24220 1.0kb upstream 1.0kb upstream 1000   false Chr4: 12563945-12564944
AT4G24220 1.0kb downstream 1.0kb downstream 2811   true Chr4: 12564945-12567755
AT4G24220 1.0kb downstream 1.0kb downstream 1000   false Chr4: 12566756-12567755
AT4G24220 3.0kb upstream 3.0kb upstream 4811   true Chr4: 12561945-12566755
AT4G24220 3.0kb upstream 3.0kb upstream 3000   false Chr4: 12561945-12564944
AT4G24220 3.0kb downstream 3.0kb downstream 4811   true Chr4: 12564945-12569755
AT4G24220 3.0kb downstream 3.0kb downstream 3000   false Chr4: 12566756-12569755


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0 Pathways

Data Source: KEGG

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10 Data Sets

Name Description Version
BAR Annotations Lookup Mapping(s) between AGI locus and Affy Probeset identifier 10/08/2013
Genome Annotation Araport11 protein-coding, non-coding and transposable element genes Araport11 (06/2016)
RNA-seq expression Measure of gene expression levels (Transcripts per Million, TPM) quantified by Salmon Araport11 (06/2016)
PubMed to gene mapping Curated associations between publications and NCBI Gene records 8/12/2016
GO Annotation from UniProt GO annotations assigned by UniProt 8/01/2016
PO Annotation from TAIR Literature-based annotations of genes to Plant Ontology (PO) terms 06/30/2015
Swiss-Prot data set High-quality, manually annotated, non-redundant protein sequence database 2016_07
Panther data set PANTHER paralogs from Arabidopsis 11.0
GeneRIF Concise phrase describing gene function and publication associated with NCBI Gene records 8/12/2016
BioGRID interaction data set Curated set of genetic and physical interactions for Arabidopsis thaliana 3.4.139